HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4'-[(2-n-Butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1H-tetrazol-5-yl)-biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4'-[(2-n-butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenyl | HCID 56999388 | — |
| Solvent | DCM ether MeOH | HCID 22565053 | — |
| Product | 4'-[(2-n-Butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1H-tetrazol-5-yl)-biphenyl | HCID 178441527 | — |
Reaction Steps
Prepared in analogous manner to Example 58b from 4'-[(2-n-butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenyl and hydrochloric acid in methylene chloride/ether/methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05541229 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-ab411d59fb6244449bdf5ed4b11e9e3a |
| Source note | uspto-grants-1996_07 |