反应详情

200 mg (0.344 mmol) of (2R*,4S*)-2-benzyl-1-(1-naphthoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted with 52 mg (1.37 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR32## is obtained as white foam. TLC: methylene chloride/methanol/conc. ammonia (1000:50:1) Rf =0.35, FD-MS: M+ =485.