Sodium borohydride → HCID 53809122, compound

Participants

Reaction Steps

160 mg (0.259 mmol) of the mixture of (2R*,4S*)-2-benzyl-1-((S)-N-acetyl-phenylalanyl)N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine diastereomers are reacted with 39 mg (1.04 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR57## is obtained as mixture of diastereomers as white foam. TLC: methylene chloride/methanol/conc. ammonia (1000:50:1) Rf =0.22, FD-MS: M+ =520.

Provenance & Evidence