Sodium borohydride → HCID 44288976, compound

Participants

Reaction Steps

254 mg (0.449 mmol) of (2R*,4S*)-2-benzyl-1-(3-chlorobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted with 68 mg (1.80 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR62## is obtained as white foam. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.29, FD-MS: M+ =470.

Provenance & Evidence