HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 57304532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzoyl chloride, 3-chloro- | HCID 69252 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Reactant | (2R*,4S*)-2-Benzyl-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine | HCID 57202094 | — |
| Product | HCID 57304532 | HCID 57304532 | — |
Reaction Steps
200 mg (0.468 mmol) of (2R*,4S*)-2-benzyl-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted in analogy to Example 35 with 72 μl (0.515 mmol) of triethylamine and 60 μl (0.468 mmol) of 3-chlorobenzoyl chloride to give the product. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.71, FD-MS: M+ =566.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05541195 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-b4de92f42d3b49179f307a8e82e7de4d |
| Source note | uspto-grants-1996_07 |