Sodium borohydride → HCID 44289232, compound

Participants

Reaction Steps

0.165 g (0.291 mmol) of (2R*,4S*)-2-benzyl-1-(2-chlorobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.044 g (1.16 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR75## is obtained (0.109 g, 80%) as white foam. TLC: methylene chloride/methanol/conc. ammonia (1000:50:1) Rf =0.33, MS: M+ =469, 471; IR: 3680, 1640, 1605, 1580 cm-1.

Provenance & Evidence