Diethyl Ether → HCID 57016239, compound

Participants

Reaction Steps

A solution of the product of Example 1 (b) (250 mg, 1.03 mmol) and methoxyamine hydrochloride (95 mg, 1.14 mmol) in pyridine (5 ml) was stirred for 48 hours. The reaction mixture was dissolved in ether (50 ml) and washed with water (2×10 ml) , 2M hydrochloric acid (2×10 ml), water (2×10 ml), saturated sodium chloride solution (10 ml) and dried over magnesium sulphate. Filtration and evaporation of the solvent under reduced pressure and silica gel chromatography yielded the title compound (56 mg).

Provenance & Evidence