HCID 10560838, compound → HCID 10584225, compound

Participants

Reaction Steps

Formamide 19 (1.00 g, 4.57 mmol) from the previous experiment is cyclized according to general procedure C to give the imine 21 as a yellow oil after FC (1:1 hexane/EtOAc, then EtOAc). The yield is 0.38 g (41%). 1H NMR (CDCl3) 8.35(s,1), 7.45-7.30(m,3), 7.16(d,1,J=7.0), 4.05-3.95(m,2), 3.80-3.70(m,2), 2.75(s,2), 1.80-1.60(m,4); 13C NMR (CDCl3) 158.21, 134.50, 131.33, 128.25, 128.05, 127.18, 127.13, 63.72, 53.85, 37.29, 37.13; MS(MW=201.3, EI, eE=70 eV) m/z 201(M+), 200, 186, 170, 156 (base peak), 144, 118, 115, 102, 89, 77, 63, 51, 41.

Provenance & Evidence