HCID 10584225, compound → HCID 10727509, compound

Participants

Reaction Steps

Imine 22 (0.430 g, 2.00 mmol) from the previous reaction is reduced according to general procedure D. The product is isolated after an acid/base work-up as described above for the reduction of 21. The resulting white crystals, mp 76-78° C., weigh 0.427 g (98%). 1H NMR(CDCl3) 7.20-7.05(m,4), 3.89(s,2), 3.88-3.75(m,2), 3.70-3.60(m,2), 2.90-2.80(m,2), 1.80-1.55(m,6), 1.23(br s,1); 13C NMR(CDCl3) 142.69, 141.94, 129.21, 127.88, 126.85, 126.00, 63.35, 52.14, 46.70, 40.44, 36.92, 29.34; MS (MW=217.3, CI/CH4, eE=120eV) m/z 218[(M+H)+, base peak], 216, 201, 183, 157, 118, 91.

Provenance & Evidence