Methoxyacetyl chloride → HCID 22611440, compound

HRID 1737769Notes

Reaction equation

HRID 1737769 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH3:18][O:19][CH2:20][C:21](Cl)=[O:22]>>[CH3:18][O:19][CH2:20][C:21]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:22]

Participants

3

Reactant 2

HCID 96623Methoxyacetyl chlorideHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611440HCID 22611440, compoundYield 84.1%

Procedure

Beginning with 13 mg (0.056 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 6.5 mg (0.059 mMol) methoxy-acetyl chloride, 14.2 mg (84%) of the title compound were recovered.

Sources & evidence

ORD record
ord-7efdc734afaa48fda37ad86ccb19de05
Source dataset
uspto-grants-1999_10
Patent number
US05962474

Reaction notes

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