Isovaleric Acid → HCID 22611380, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[C:18](O)(=[O:23])[CH2:19][CH:20]([CH3:22])[CH3:21]>>[CH3:21][CH:20]([CH3:22])[CH2:19][C:18]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:23]Participants
3
Procedure
Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 10.0 mg (0.10 mMol) isovaleric acid, 17.0 mg (100+%) of the title compound were recovered.
Sources & evidence
- ORD record
- ord-cd73cfc3a9264c09b9971854ce5d70ca
- Source dataset
- uspto-grants-1999_10
- Patent number
- US05962474
Reaction notes
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