Water → HCID 178443821, compound

Participants

Reaction Conditions

Reaction Steps

8.3 g of 5-amino-2-mercaptobenzimidazole was suspended in a mixture of 20 ml of dimethylacetamide and 35 ml of acetonitrile. 8.5 g of octanoyl chloride was dropped into the suspension at 50° C. After stirring at 50° C. for 2 hours, 20 ml of water was added to the reaction mixture. Crystals thus formed were collected by filtration, washed with water and dried to obtain 12.8 g of 2-mercapto-5-octanamidobenzimidazole (yield: 88%).

Provenance & Evidence