Carbon Tetrachloride → HCID 131721395, compound

Participants

Reaction Steps

Trifluoroacetic acid (3 mL) was added to a solution of CBZ-L-Leu-L-Pip-OtBu (0.57 g, 1.3 mmol) in CH2Cl2 (6 mL) at 23° C. The reaction mixture was stirred at 23° C. for 1.5 h after which CCl4 (6 mL) was added. The volatiles were then removed under reduced pressure to afford crude CBZ-L-Leu-L-Pip as a colorless oil. The crude acid thus obtained was immediately utilized in the following coupling procedure.

Provenance & Evidence