HCID 21843579, compound → HCID 10709714, compound

HRID 1737866Notes

Reaction equation

HRID 1737866 reaction equation
Cl[CH:2]([C:12]1[CH:17]=[CH:16][C:15]([C:18]#[N:19])=[CH:14][CH:13]=1)[CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([F:11])=[CH:7][CH:6]=1.[Na].[NH:21]1[CH:25]=[CH:24][N:23]=[CH:22]1>>[C:18]([C:15]1[CH:16]=[CH:17][C:12]([CH:2]([N:21]2[CH:25]=[CH:24][N:23]=[CH:22]2)[CH2:3][CH2:4][C:5]2[CH:10]=[CH:9][C:8]([F:11])=[CH:7][CH:6]=2)=[CH:13][CH:14]=1)#[N:19]

Participants

3

Reactant 2

HCID 21843579HCID 21843579, compoundHCID 57373095Imidazole sodium

Product 1

HCID 10709714HCID 10709714, compound

Procedure

1-[1-(4-cyanophenyl)-3-(4-fluorophenyl)propyl]-1H-imidazole is prepared according to the same procedure using 1-chloro-1-(4cyanophenyl)-3-(4-fluorophenyl)propane and 1H-imidazole sodium derivative as starting materials.

Sources & evidence

ORD record
ord-c4dadcde9eed4b89aa4d956a07375302
Source dataset
uspto-grants-1999_10
Patent number
US05962495

Reaction notes

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