Hydrochloric Acid → HCID 178418437, compound

Participants

Reaction Steps

A solution of 0.39 g (0.001 mol) of trans-O-(4-chlorophenylacetyl)-4-(4-dimethylaminomethylphenyl)-cyclohexanol in 10 ml of diethyl ether is combined at ambient temperature, with stirring, with a 1.5 times equimolar amount of hydrogen chloride in isopropanol added dropwise. The precipitate formed is left for 1 hour at ambient temperature, suction filtered, washed repeatedly with diethyl ether and dried. White crystals are obtained, melting point 231-233° C. Yield: 0.32 g (76% of theory). C23H29Cl2NO2 (422.40) Calculated: C 65.40 H 6.92 N 3.32 Cl 16.79 Found: 65.33 7.06 3.45 16.92

Provenance & Evidence