Cycloheptanecarbonyl chloride → HCID 21843741, compound

HRID 1737945Notes

Reaction equation

[NH2:1][CH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[O:4]1.[CH:15]1([C:22](Cl)=[O:23])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[CH3:14][O:13][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]2[C:5]=1[O:4][CH:3]([CH2:2][NH:1][C:22]([CH:15]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1)=[O:23])[CH2:12][CH2:11]2

Participants

Reactant 2

HCID 12556870Cycloheptanecarbonyl chloride

HCID 15057554HCID 15057554, compound

Product 1

HCID 21843741HCID 21843741, compound

Procedure

The title compound is prepared analogously to the instructions of Example XII from 2-aminomethyl-8-methoxy-chroman and cycloheptanecarbonyl chloride, and is further reacted directly.

Workup

customis further reacted directly

Sources & evidence

ORD record: ord-06f69a5824054d00bfc66b97453c6959
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05962513

Reaction notes

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