Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 173797Generated: October 25, 2026

Tetrahydrofuran → 1-Benzyl-4-(2-fluoro-5-methylbenzyl)piperidin-4-ol

https://huagongshe.com/reaction/173797

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant6-Benzyl-1-oxa-6-azaspiro(2,5)octaneHCID 89238—
Reactant3-Bromo-4-fluorotolueneHCID 96745—
ReactantButyllithiumHCID 178418339—
Product1-Benzyl-4-(2-fluoro-5-methylbenzyl)piperidin-4-olHCID 59833635—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-c81e09234f204186a6171612893f2ca8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)