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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1737992Generated: October 25, 2026

Carbamic chloride, N-methyl-N-phenyl- → N-methyl-N-phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)urea

https://huagongshe.com/reaction/1737992

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic chloride, N-methyl-N-phenyl-HCID 77969—
Reactant3-(1-Methylpiperidin-4-yl)-1h-indol-5-amineHCID 11831220—
ProductN-methyl-N-phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ureaHCID 22611656—

Reaction Steps

Beginning with 13.0 mg (0.056 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 10.1 mg (0.059 mMol) N-methyl-N-phenyl carbamoyl chloride, 17.4 (86%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05962473
Source datasetuspto-grants-1999_10
ORD IDord-555cbd56a32a40258ebce36cafd9701e
Source noteuspto-grants-1999_10