HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → N-[3-(1-Methylpiperidin-4-yl)-1H-indol-5-yl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 86751892 | HCID 86751892 | — |
| Product | N-[3-(1-Methylpiperidin-4-yl)-1H-indol-5-yl]acetamide | HCID 22611622 | 78.3% |
Reaction Steps
Beginning with 2.00 gm (5.74 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole dihydrochloride ethanolate and 1.13 gm (25.8 mMol) acetyl chloride, 1.22 gm (78.3%) of the title compound were recovered as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05962473 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-8cc981dda0e749c0b9c08dab1b86c4e1 |
| Source note | uspto-grants-1999_10 |