Quinaldic Acid → HCID 22611208, compound

HRID 1738056Notes

Reaction equation

HRID 1738056 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH:18]1[CH:23]=[C:22]2[CH:24]=[CH:25][C:26]([C:28](O)=[O:29])=[N:27][C:21]2=[CH:20][CH:19]=1>>[N:27]1[C:21]2[C:22](=[CH:23][CH:18]=[CH:19][CH:20]=2)[CH:24]=[CH:25][C:26]=1[C:28]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:29]

Participants

3

Reactant 2

HCID 7124Quinaldic AcidHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611208HCID 22611208, compoundYield 92%

Procedure

Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 17.0 mg (0.10 mMol) 2-quinaldic acid, 17.6 mg (92%) of the title compound were recovered.

Sources & evidence

ORD record
ord-fd5077636e6c4ca5971dd01b799d3fa1
Source dataset
uspto-grants-1999_10
Patent number
US05962473

Reaction notes

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