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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 173847Generated: October 26, 2026

Methyl 3-Hydroxyphenylacetate → 2-Methyl-2-(3-{[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylcarbamoyl]-methyl}-phenoxy)-propionic acid tert-butyl ester

https://huagongshe.com/reaction/173847

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-HydroxyphenylacetateHCID 39129—
Reactanttert-Butyl 2-bromo-2-methylpropionateHCID 90290—
Reactant3-(1-tert-Butoxycarbonyl-1-methylethoxy)phenylacetic AcidHCID 18766414—
Reactant2-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amineHCID 21935832—
Product2-Methyl-2-(3-{[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylcarbamoyl]-methyl}-phenoxy)-propionic acid tert-butyl esterHCID 67072142—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-97f75b81a137494a8ec91a778790ada1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)