HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 2-Ethyl-5-methylbenzo[b]thiophene | HCID 595344 | — |
| Product | 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride | HCID 22998437 | — |
Reaction Steps
2-ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride was prepared in the same manner as described in Example 40B. Reaction of DMF (6.5 mmoles, 0.50 ml), sulfurylchloride (5.5 mmoles, 0.44 ml) and 2-ethyl-5-methylbenzo[b]thiophene (3.2 mmoles, 0.57 g) yielded, after flash chromatography, using 2% ethyl acetate/hexanes, 0.58 g (66%) of an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05962490 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-f92277a6d42e49f09c46e0a70bd56245 |
| Source note | uspto-grants-1999_10 |