HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-(4-Methoxybenzyl)benzo[b]thiophene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | a-(2-Benzo[b]thienyl)-4-methoxybenzyl alcohol | HCID 49962600 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(4-Methoxybenzyl)benzo[b]thiophene | HCID 22998384 | — |
Reaction Steps
2-(4-methyoxybenzyl)-benzo[b]thiophene was prepared by the method of Example 47B with α-(2-benzo[b]thienyl)-4-methoxybenzyl alcohol (1.9 mmoles) 0.50 g), triethysilane (2.0 mmoles, 0.32 mls), CH2Cl2 (20 ml) and TFA (3.7 mmoles, 0.30 ml). Recrystallization with hexanes and chloroform provided 0.40 (85%) of a pink solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05962490 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-38d6eaf8d6464655b614aa75680da9d8 |
| Source note | uspto-grants-1999_10 |