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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1738529Generated: October 31, 2026

Sulfuryl chloride → HCID 23445551, compound

https://huagongshe.com/reaction/1738529

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfuryl chlorideHCID 24648—
ReactantPotassiumHCID 5462222—
ReactantHCID 23445359HCID 23445359—
ProductHCID 23445551HCID 2344555142%

Reaction Steps

3-chlorosulfonyl-2-[3,4-(methylenedioxy)phenethyl]thiophene was prepared in the same manner as described in the Example 64E using N-{2-[3,4-(methylenedioxy)phenethyl]thiophene-3-sulfonyl}pyrrole by conducting basic hydrolysis (iso-propanol and potassium hydroxide) of the sulfonamide to the potassium salt of sulfonic acid (93%) followed by conversion of the salt to the corresponding sulfonyl chloride in a 42% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05962490
Source datasetuspto-grants-1999_10
ORD IDord-84a7b5a3613b4d83a55db58ec4d22d31
Source noteuspto-grants-1999_10