1-(Chloromethoxy)-2-methoxyethane → HCID 69983700, compound

HRID 1738532Notes

Reaction equation

HRID 1738532 reaction equation
[CH3:1][C:2]1[C:6]([CH3:7])=[C:5]([NH:8][S:9]([C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)(=[O:11])=[O:10])[O:4][N:3]=1.[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22]Cl>>[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22][N:8]([C:5]1[O:4][N:3]=[C:2]([CH3:1])[C:6]=1[CH3:7])[S:9]([C:12]1[S:13][CH:14]=[CH:15][CH:16]=1)(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 22998429HCID 22998429, compound

Product 1

HCID 69983700HCID 69983700, compoundYield 34%

Procedure

N-(methyoxyethoxymethyl)-N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide was prepared in the same manner as described in Example 32B using N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide and methoxyethoxymethyl chloride resulting in 34% yield. HPLC analysis of the crude oil obtained after workup showed that the oil was approximately 96% pure and so was used in the next step without further purification.

Workup

  1. customHPLC analysis of the crude oil obtained after workup
  2. customso was used in the next step without further purification

Sources & evidence

ORD record
ord-e19c5361e44d4974883cc755a2827b02
Source dataset
uspto-grants-1999_10
Patent number
US05962490

Reaction notes

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