1,3-Benzodioxol-5-amine → HCID 23288577, compound

HRID 1738645Notes

Reaction equation

HRID 1738645 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[CH:16]=[C:17]([CH:21]=[C:22]([O:33][CH2:34][CH2:35][OH:36])[C:23]=2[O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([O:31][CH3:32])[CH:26]=2)[C:18](O)=[O:19])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH2:37]1[O:46][C:45]2[CH:44]=[CH:43][C:41]([NH2:42])=[CH:40][C:39]=2[O:38]1>>[O:46]1[C:45]2[CH:44]=[CH:43][C:41]([NH:42][C:18](=[O:19])[C:17]3[CH:21]=[C:22]([O:33][CH2:34][CH2:35][OH:36])[C:23]([O:24][C:25]4[CH:30]=[CH:29][CH:28]=[C:27]([O:31][CH3:32])[CH:26]=4)=[C:15]([NH:14][S:11]([C:8]4[CH:9]=[CH:10][C:5]([C:1]([CH3:3])([CH3:2])[CH3:4])=[CH:6][CH:7]=4)(=[O:12])=[O:13])[CH:16]=3)=[CH:40][C:39]=2[O:38][CH2:37]1

Participants

3

Reactant 2

HCID 843101,3-Benzodioxol-5-amineHCID 17878578HCID 17878578, compound

Product 1

HCID 23288577HCID 23288577, compound

Procedure

Analogously to Example 74, by condensing 3-(4-tert-butyl-benzenesulphonylamino)-5-(2-hydroxy-ethoxy)-4-(3-methoxy-phenoxy)-benzoic acid with 3,4-methylenedioxyaniline there was obtained N-benzo-[1,3]dioxol-5-yl-3-(4-tert-butylbenzenesulphonylamino)-5-(2-hydroxy-ethoxy)-4-(3-methoxy-phenoxy)-benzamide.

Sources & evidence

ORD record
ord-6ee3bdd5cd4647559e645947e607495e
Source dataset
uspto-grants-1999_10
Patent number
US05962682

Reaction notes

Loading…