HCID 17878592, compound → HCID 178491313, compound

HRID 1738654Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[CH:16]=[C:17]([CH:21]=[C:22]([O:33][CH2:34][CH:35]([OH:38])[CH2:36][OH:37])[C:23]=2[O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([O:31][CH3:32])[CH:26]=2)[C:18](O)=[O:19])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH2:39][C:40]1[NH:44][N:43]=[N:42][N:41]=1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[CH:16]=[C:17]([CH:21]=[C:22]([O:33][CH2:34][CH:35]([OH:38])[CH2:36][OH:37])[C:23]=2[O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([O:31][CH3:32])[CH:26]=2)[C:18]([NH:39][C:40]2[NH:44][N:43]=[N:42][N:41]=2)=[O:19])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 17878592HCID 17878592, compound

HCID 178509299HCID 178509299, compound

Product 1

HCID 178491313HCID 178491313, compound

Procedure

In analogy to Example 121, by coupling 3-(4-tert-butyl-benzenesulphonylamino)-5-(2,3-dihydroxy-propoxy)-4-(3-methoxy-phenoxy)-benzoic acid with 5-aminotetrazole there was obtained 3-(4-tert-butybenzenesulphonylamino)-5-(2,3-dihydroxy-propoxy)-4-(3-methoxy-phenoxy)-N-(1H-tetrazol-5-yl)-benzamide as a white solid.

Sources & evidence

ORD record: ord-61d1c3ae615e4c0fb8a8d45126b731d1
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05962682

Reaction notes

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