HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fumaric Acid → HCID 21839358, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-1-(4-oxopentyl)-7-propyl- | HCID 3059109 | — |
| Reactant | 1-Methyl-4-(prop-2-yn-1-yl)piperazine | HCID 13514091 | — |
| Product | HCID 21839358 | HCID 21839358 | 82% |
Reaction Steps
1-(4-Hydroxy-4-methyl-7-[4-methylpiperazino]-5-heptynyl)-3-methyl-7-propylxanthine was prepared as oily substance in 82% yield using 3-methyl-1-(4-oxopentyl)-7-propylxanthine and 4-methyl-1-(2-propynyl)-piperazine from stage C1) as in Example 6C1). Salt formation with fumaric acid took place as in Example 7F2) in 55% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05965555 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-23aebe739e4442898971935e3fb92e0c |
| Source note | uspto-grants-1999_10 |