N,N-Dipropyl-2-propyn-1-amine → HCID 15390918, compound

HRID 1738799Notes

Reaction equation

HRID 1738799 reaction equation
[CH2:1]([N:5]1[C:13]2[N:12]=[CH:11][N:10]([CH2:14][CH2:15][CH3:16])[C:9]=2[C:8](=[O:17])[N:7]([CH2:18][CH2:19][C:20](=[O:22])[CH3:21])[C:6]1=[O:23])[CH2:2][CH2:3][CH3:4].[CH2:24]([N:27]([CH2:31][C:32]#[CH:33])[CH2:28][CH2:29][CH3:30])[CH2:25][CH3:26]>>[CH2:1]([N:5]1[C:13]2[N:12]=[CH:11][N:10]([CH2:14][CH2:15][CH3:16])[C:9]=2[C:8](=[O:17])[N:7]([CH2:18][CH2:19][C:20]([OH:22])([CH3:21])[C:33]#[C:32][CH2:31][N:27]([CH2:28][CH2:29][CH3:30])[CH2:24][CH2:25][CH3:26])[C:6]1=[O:23])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 138724N,N-Dipropyl-2-propyn-1-amineHCID 15390930HCID 15390930, compound

Product 1

HCID 15390918HCID 15390918, compoundYield 28%

Procedure

3-Butyl-1-(6-dipropylamino-3-hydroxy-3-methyl-4-hexynyl)-7-propylxanthine was prepared in 28% yield using 3-butyl-1-(3-oxobutyl)-7-propylxanthine and N,N-dipropyl-2-propynylamine as as in Example 6C1).

Sources & evidence

ORD record
ord-a742250867534699ae4d5f8e44e1d144
Source dataset
uspto-grants-1999_10
Patent number
US05965555

Reaction notes

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