Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1738850Generated: November 4, 2026

Ethyl 1-benzylpiperazine-2-carboxylate → HCID 22721873, compound

https://huagongshe.com/reaction/1738850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1-benzylpiperazine-2-carboxylateHCID 10682021—
Reactant1-(4-Pyridinyl)-4-piperidinecarbonyl chlorideHCID 11183700—
ProductHCID 22721873HCID 2272187367%

Reaction Steps

Using an analogous procedure to that described in Example 1, 1-(4-pyridyl)piperidine-4-carbonyl chloride was reacted with ethyl 1-benzylpiperazine-2-carboxylate (Helv. Chim. Acta, 1962, 45, 2383) to give 1-benzyl-2-ethoxycarbonyl-4-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine in 67% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05965559
Source datasetuspto-grants-1999_10
ORD IDord-b80692001c444699b6b9f02e07a5120a
Source noteuspto-grants-1999_10