HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 1-Hydrazino-2-methyl-4-nitrobenzene hydrofluoride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Benzene, 1-fluoro-2-methyl-4-nitro- | HCID 68001 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 1-Hydrazino-2-methyl-4-nitrobenzene hydrofluoride | HCID 22111787 | — |
Reaction Steps
A mixture of 4.6 g of 1-fluoro-2-methyl-4-nitrobenzene and 3 ml of hydrazine hydrate in 45 ml of 2-propanol is heated to reflux for 2 hours. 3 ml of hydrazine hydrate are added, refluxing is continued for 2 hours and the mixture is left overnight with stirring at RT. The precipitate formed is drained. 3.53 g of the expected product are obtained, m.p.=182° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05965579 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-92ab1c578bc14a9ebda92fd4f58d4468 |
| Source note | uspto-grants-1999_10 |