HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Benzenesulfonamide, 4-methyl-N-(4-nitrophenyl)- | HCID 69772 | — |
| Reactant | HCID 178418368 | HCID 178418368 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide | HCID 22111802 | — |
Reaction Steps
This compound is prepared according to the procedure described in step A of Preparation 2.18, from 10 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 42.6 ml of a 2M solution of isobutylmagnesium chloride in ether, followed by 4.4 ml of bromine and 23.4 ml of triethylamine. 5.9 g of the expected product are obtained, m.p.=170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05965579 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-b4a2a704465c4967897c215155437146 |
| Source note | uspto-grants-1999_10 |