Potassium Bromide → HCID 23221715, compound

Participants

Reaction Steps

A pinch of tetramethylpyridine N-oxide and 10 ml of 12.5% strength sodium hypochlorite solution are added to a stirred mixture of 3 g (16 mmol) of methyl (2-methylpyrid-3-yl)-α-hydroxyacetate (Example 1b) in 20 ml of methylene chloride and 0.5 g (3.5 mmol) of Na2HPO4, 0.6 g (5 mmol) of NaH2PO4 and 0.2 g (1.6 mmol) of KBr in 20 ml of water. Stirring is carried out for 1 hour at room temperature, after which the organic phase is separated off and evaporated down. 2.2 g (77%) of the title compound are obtained as residual yellow oil.

Provenance & Evidence