Thiazolidinedione → HCID 10870955, compound

HRID 1739020Notes

Reaction equation

HRID 1739020 reaction equation
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[CH:15]=O)=[CH:7][CH:6]=1)([CH3:3])[CH3:2].[S:17]1[CH2:21][C:20](=[O:22])[NH:19][C:18]1=[O:23]>>[CH:1]([O:4][C:5]1[CH:6]=[CH:7][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:21]2[S:17][C:18](=[O:23])[NH:19][C:20]2=[O:22])=[CH:9][CH:10]=1)([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 10954968HCID 10954968, compound

Product 1

HCID 10870955HCID 10870955, compoundYield 26%

Procedure

According to the same manner as that described in Example 23, (E,E)-5-(4-isopropoxyphenyl)-2,4-pentadienal was condensed with 2,4-thiazolidinedione, and the resulting compound was subjected to catalytic hydrogenation to give 5-[5-(4-isopropoxyphenyl)pentyl]-2,4-thiazolidinedione as an oil (yield: 26%).

Sources & evidence

ORD record
ord-4872beb6690b401d8505eef13c6b7595
Source dataset
uspto-grants-1999_10
Patent number
US05965589

Reaction notes

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