Thiazolidinedione → HCID 54461797, compound

HRID 1739021Notes

Reaction equation

[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:13][O:14][C:15]1[CH:16]=[C:17]2[C:22](=[CH:23][CH:24]=1)[CH:21]=[C:20]([CH:25]=O)[CH2:19][CH2:18]2.[S:27]1[CH2:31][C:30](=[O:32])[NH:29][C:28]1=[O:33]>>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH2:13][O:14][C:15]1[CH:16]=[C:17]2[C:22](=[CH:23][CH:24]=1)[CH:21]=[C:20]([CH:25]=[C:31]1[S:27][C:28](=[O:33])[NH:29][C:30]1=[O:32])[CH2:19][CH2:18]2

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 21840249HCID 21840249, compound

Product 1

HCID 54461797HCID 54461797, compoundYield 50%

Procedure

According to the same manner as that described in Example 1, 6-(5-methyl-2-phenyl-4-oxazolylmethoxy)-3,4-dihydro-2-naphthoaldehyde was condensed with 2,4-thiazolidinedione to give 5-[6-(5-methyl-2-phenyl-4-oxazolylmethoxy)-3,4-dihydro-2-naphthylmethylidene]-2,4-thiazolidinedione (yield: 50%). This product was recrystallized from dichloromethane-methanol. Yellow needles, mp: 271-272° C.

Sources & evidence

ORD record: ord-ee856e0328f944da8aeb085d34e0e2f7
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05965589

Reaction notes

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