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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1739024Generated: November 4, 2026

Thiazolidinedione → HCID 86754592, compound

https://huagongshe.com/reaction/1739024

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazolidinedioneHCID 5437—
ReactantHCID 54250395HCID 54250395—
ProductHCID 86754592HCID 8675459231%

Reaction Steps

According to the same manner as that described in Example 13, 4-(5-methyl-2-phenyl-4-oxazolylmethoxy)-3-trifluoromethylcinnamaldehyde was condensed with 2,4-thiazolidinedione, and the resulting product was subjected to catalytic hydrogenation to give 5-[3-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)-3-trifluoromethylphenyl]propyl]-2,4-thiazolidinedione (yield: 31%). This product was recrystallized from dichloromethane-methanol. Colorless prisms, mp: 154-155° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05965589
Source datasetuspto-grants-1999_10
ORD IDord-f1d7b94f7c1b41dfaf05635c13a6bec7
Source noteuspto-grants-1999_10