Thiazolidinedione → HCID 57160713, compound

HRID 1739027Notes

Reaction equation

[CH:1]([O:4][C:5]1[CH:14]=[CH:13][C:8]([CH:9]=[CH:10][CH:11]=O)=[CH:7][C:6]=1[O:15][CH3:16])([CH3:3])[CH3:2].[S:17]1[CH2:21][C:20](=[O:22])[NH:19][C:18]1=[O:23]>>[CH:1]([O:4][C:5]1[CH:14]=[CH:13][C:8]([CH:9]=[CH:10][CH:11]=[C:21]2[S:17][C:18](=[O:23])[NH:19][C:20]2=[O:22])=[CH:7][C:6]=1[O:15][CH3:16])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 54522834HCID 54522834, compound

Product 1

HCID 57160713HCID 57160713, compoundYield 61%

Procedure

According to the same manner as that described in Example 1, 4-isopropoxy-3-methoxycinnamaldehyde was condensed with 2,4-thiazolidinedione to give 5-(4-isopropoxy-3-methoxycinnamylidene)-2,4-thiazolidinedione (yield: 61%). This product was recrystallized from ethyl acetate-hexane. Yellow prisms, mp: 230-231° C.

Sources & evidence

ORD record: ord-72ebb94cb98a4c849691610a92085e59
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05965589

Reaction notes

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