反应详情

Activated manganese dioxide (25.0 g) was added to a solution of (E)-3-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)-phenyl]-2-propenol (11.0 g) in dichloromethane (200 ml), and the mixture was stirred at room temperature for 2 hours. The insoluble materials were filtered off, and the filtrate was concentrated under reduced pressure to give 3-(5-methyl-2-phenyl-4-oxazolylmethoxy)cinnamaldehyde (10.5 g, 96%). This product was recrystallized from ethyl acetate-hexane. Colorless columns, mp: 103-104° C.

1. filtrationThe insoluble materials were filtered off
2. concentrationthe filtrate was concentrated under reduced pressure