HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethyl phosphonoacetate → Methyl 3-methoxy-4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]cinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethyl phosphonoacetate | HCID 80029 | — |
| Reactant | 4-[2-(2-Furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxybenzaldehyde | HCID 22344630 | — |
| Product | Methyl 3-methoxy-4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]cinnamate | HCID 54365390 | 90% |
Reaction Steps
According to the same manner as that described in Reference Example 1, 3-methoxy-4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]benzaldehyde was reacted with trimethyl phosphonoacetate to give methyl 3-methoxy-4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]cinnamate (yield: 90%). This product was recrystallized from dichloromethane-diethyl ether. Colorless prisms, mp: 129-130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05965589 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-3e6186fa4bc24f01a74e685f0a539e11 |
| Source note | uspto-grants-1999_10 |