HCID 86754597, compound → HCID 86754596, compound

HRID 1739047Notes

Reaction equation

HRID 1739047 reaction equation
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][CH2:13][CH:14]2[S:18][C:17](=[O:19])[NH:16][C:15]2=[O:20])=[CH:7][C:6]=1[O:21][CH3:22])(C)C>[Ti](Cl)(Cl)(Cl)Cl>[OH:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][CH2:13][CH:14]2[S:18][C:17](=[O:19])[NH:16][C:15]2=[O:20])=[CH:7][C:6]=1[O:21][CH3:22]

Participants

3

Reactant 1

HCID 86754597HCID 86754597, compound

Product 1

HCID 86754596HCID 86754596, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 24193Titanium TetrachlorideCatalyst

Procedure

According to the same manner as that described in Reference Example 37, 5-[3-(4-isopropoxy-3-methoxyphenyl)-propyl]-2,4-thiazolidinedione was treated with titanium tetrachloride to give 5-[3-(4-hydroxy-3-methoxyphenyl)propyl]-2,4-thiazolidinedione as an oil (yield: 87%).

Sources & evidence

ORD record
ord-d7a80dbb21664e378c640bd65a9739e6
Source dataset
uspto-grants-1999_10
Patent number
US05965589

Reaction notes

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