HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Methionine → HCID 67565913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Methionine | HCID 6137 | — |
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | (+)-L-Leucine methyl ester | HCID 65105 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | HCID 67565265 | HCID 67565265 | — |
| Product | HCID 67565913 | HCID 67565913 | — |
Reaction Steps
This compound was prepared with the same method as for the preparation of the methionine derivative (section J) using 4-nitro-2-naphthylbenzoic acid, (S)-leucine methyl ester, EDCI and HOBT. 1H NMR (CDCl3) δ 8.34-8.39 (m, 1H), 8.25 (s, 1H), 8.18 (d, 8.6 Hz, 0.6H), 8.02 (d, 8.6 Hz, 0.4H), 7.91-8.00 (m, 2H), 7.62 (t, 7.0 Hz, 0.6H), 7.48-7.58 (m, 3H), 7.41 (t, 7.0 Hz, 1.4H), 5.71 (d, 7.9 Hz, 0.6H), 5.60 (d, 7.9 Hz, 0.4H), 4.29 (m, 1H), 3.57 (s, 1.7H), 3.52 (s, 1.3H), 1.05-1.11 (m, 0.5H), 0.88-0.97 (m, 0.7H), 0.69-0.78 (m, 0.5H), 0.41-0.59 (m, 7.0H), 0.19-0.26 (m, 0.6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05965539 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-2aedc503eb81440ba402a980869c711b |
| Source note | uspto-grants-1999_10 |