Benzophenone → 99046-40-9

HRID 1739160Notes

Reaction equation

COC.[NH2:4][S:5]([C:8]1[CH:13]=[CH:12][C:11](/[CH:14]=[C:15]2/[C:16]([CH3:30])=[C:17]([CH2:26][CH2:27][O:28][CH3:29])[C:18]3[C:23]/2=[CH:22][CH:21]=[C:20]([O:24][CH3:25])[CH:19]=3)=[CH:10][CH:9]=1)(=[O:7])=[O:6].C(C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[NH2:4][S:5]([C:8]1[CH:13]=[CH:12][C:11](/[CH:14]=[C:15]2\[C:16]([CH3:30])=[C:17]([CH2:26][CH2:27][O:28][CH3:29])[C:18]3[C:23]\2=[CH:22][CH:21]=[C:20]([O:24][CH3:25])[CH:19]=3)=[CH:10][CH:9]=1)(=[O:6])=[O:7]

Participants

Reactant 3

HCID 3102Benzophenone

HCID 8254Dimethyl Ether

HCID 13933281HCID 13933281, compound

Product 1

HCID 643881899046-40-9Yield 13%

Procedure

A solution of the Z methyl ether, E 1-(4-aminosulfonylphenyl)-methylene-5-methoxy-2-methyl-1H-3-indenyl-(2-methoxy)ethane (17a) (700 mg) and benzophenone (3.5 g) was irradiated with a medium pressure Hanovia lamp (450 watt) through a quartz well for 75 minutes under nitrogen. Following the work up procedure of Method A, there was obtained E 1-(4-aminosulfonylphenyl)methylene-5-methoxy-2-methyl-1H-3-indenyl-(2-methoxy)ethane (18a) (90 mg, 13% yield): m.p. 139.5°-140.0° C.

Sources & evidence

ORD record: ord-6cc4d6f3aaf140d888223255fc2956c4
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05965619

Reaction notes

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