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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 173932Generated: October 25, 2026

Hydrochloric Acid → (7RS,9aSR)-7-hydroxymethyl-2-(2-cyano4-fluorophenyl)-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazine

https://huagongshe.com/reaction/173932

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethyl SulfoxideHCID 679—
Reactant2,5-DifluorobenzonitrileHCID 123558—
Reactant(Octahydro-1H-pyrido[1,2-A]pyrazin-7-YL)methanolHCID 12985539—
Product(7RS,9aSR)-7-hydroxymethyl-2-(2-cyano4-fluorophenyl)-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazineHCID 69432665—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-1927896b61ad4cecbf2833ec66af2205
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)