Hydrogen Bromide → 1-Bromo-4-phenylbutane

Participants

Reaction Steps

To 1.0 g of 4-phenyl-1-butanol, were added 0.33 g of concentrated sulfuric acid and 1.7 g of 47% aqueous solution of hydrobromic acid, and the resultant solution was then stirred for 5 hours at a temperature of from 140 to 150° C. while applying heating. The solution reacted was then poured into ice water and extracted with ethyl acetate. The organic layer resulted was dried with anhydrous magnesium sulfate, and the solvent used was removed by distillation under reduced pressure, thereby affording 1.25 g of 4-phenyl-1-bromobutane.

Provenance & Evidence