反应详情

2.9 g of 4-(4-phenylbutyloxy)benzyl alcohol were dissolved in 30 ml of chloroform, and 1.6 g of thionyl chloride were further fed dropwise to the resultant solution. The solution was then stirred for 1 hour at room temperature. After completed the reaction, the solution reacted was poured into ice-water and extracted with chloroform. The organic layer resulted was dried with anhydrous magnesium sulfate, and the solvent used was removed by distillation under reduced pressure, thereby affording 3.2 g of 4-(4-phenylbutyloxy)benzyl chloride.

1. customthe reaction
2. customthe solution reacted
3. extractionextracted with chloroform
4. customThe organic layer resulted
5. dry with materialwas dried with anhydrous magnesium sulfate
6. customthe solvent used was removed by distillation under reduced pressure