HCID 11472725, compound → HCID 21840862, compound

HRID 1739417Notes

Reaction equation

HRID 1739417 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]2[C:18]3[C:13](=[CH:14][C:15]([O:22][CH2:23][CH3:24])=[C:16]([O:19][CH2:20][CH3:21])[CH:17]=3)[CH:12]=[C:11]([CH2:25][OH:26])[N:10]=2)[CH:6]=[CH:5][N:4]=1)[NH2:2].[CH3:27][O:28][C:29]1[CH:30]=[C:31]([CH:42]=[C:43]([O:47][CH3:48])[C:44]=1[O:45][CH3:46])[C:32]([C:34]1[S:35][CH:36]=[CH:37][C:38]=1[C:39](O)=[O:40])=O>>[OH:26][CH2:25][C:11]1[N:10]=[C:9]([C:7]2[CH:6]=[CH:5][N:4]=[C:3]([N:1]3[C:39](=[O:40])[C:38]4[CH:37]=[CH:36][S:35][C:34]=4[C:32]([C:31]4[CH:42]=[C:43]([O:47][CH3:48])[C:44]([O:45][CH3:46])=[C:29]([O:28][CH3:27])[CH:30]=4)=[N:2]3)[CH:8]=2)[C:18]2[C:13]([CH:12]=1)=[CH:14][C:15]([O:22][CH2:23][CH3:24])=[C:16]([O:19][CH2:20][CH3:21])[CH:17]=2

Participants

3

Reactant 2

HCID 11472725HCID 11472725, compoundHCID 21840819HCID 21840819, compound

Product 1

HCID 21840862HCID 21840862, compound

Procedure

2-Hydrazino-4-(3-hydroxymethyl-6,7-diethoxyisoquinolin-1-yl)pyridine and 2-(3,4,5-trimethoxybenzoyl)-3-thiophenecarboxylic acid are treated in the same manner as in Example 7-(4) to give 4-(3-hydroxymethyl-6,7-diethoxyisoquinolin-1-yl)-2-[7-(3,4,5-trimethoxyphenyl)thieno[2,3-d]pyridazin-4(5H)-on-5-yl]pyridine.

Sources & evidence

ORD record
ord-ec53110ab79147c886b440e861f9ce44
Source dataset
uspto-grants-1999_10
Patent number
US05965730

Reaction notes

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