5-fluoro-1-benzothiophene-2-carboxylic acid → HCID 21841161, compound

HRID 1739453Notes

Reaction equation

HRID 1739453 reaction equation
[F:1]C1C=CC2SC(C(O)=O)=CC=2C=1.F[C:15]1[CH:28]=[CH:27][C:18]2[S:19][C:20]([C:22]([S:24][CH2:25][CH3:26])=[S:23])=[CH:21][C:17]=2[CH:16]=1>>[F:1][C:16]1[C:17]2[CH:21]=[C:20]([C:22]([S:24][CH2:25][CH3:26])=[S:23])[S:19][C:18]=2[CH:27]=[CH:28][CH:15]=1

Participants

3

Reactant 2

HCID 9014395-fluoro-1-benzothiophene-2-carboxylic acidHCID 21841166HCID 21841166, compound2×

Product 1

HCID 21841161HCID 21841161, compound

Procedure

The 5-fluoro-2-benzo[b]thiophenecarboxylic acid prepared above in A was converted to ethyl 5-fluoro-2-benzo[b]thiophenecarbodithioate (mp 91-92° C.) using the procedures described above in Examples 2(B)-2(D). NMR confirmed the structure as that of ethyl 5-fluoro-2-benzo[b]thiophenecarbodithioate.

Sources & evidence

ORD record
ord-bd946c624e7f4247883a3c35018f4e9b
Source dataset
uspto-grants-1999_10
Patent number
US05965749

Reaction notes

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