反应详情

In chloroform (50 ml), 5-ethyl-2-imino-3-(4-iodobenzyl)-1,3,4-thiadiazoline hydrobromide (2.89 g) was suspended. To the resulting suspension was added 0.5N sodium hydroxide (25 ml), and they were stirred for 30 minutes. After separation, the organic layer was dried over anhydrous magnesium sulfate. The oily substance so obtained was crystallized from diisopropyl ether, whereby 1.85 g of the title compound was obtained.

1. customAfter separation
2. dry with materialthe organic layer was dried over anhydrous magnesium sulfate
3. customThe oily substance so obtained
4. customwas crystallized from diisopropyl ether