Water → HCID 21835877, compound

Participants

Reaction Conditions

Reaction Steps

20.6 g of 4'-vinylbicyclohexyl-4-one and 39.7 g of triphenyl(3-butenyl)phosphonium bromide in 250 ml of THF were cooled to -10° C. under nitrogen with stirring. A solution of 11.44 g of potassium tert-butoxide in 150 ml of THF was then added dropwise at -10° C. with stirring, and the mixture was then stirred at RT for a further 2 hours. The yellow suspension was cooled to 10° C., and 500 ml of water were added. The organic phase was separated off, and the aqueous phase was extracted once with 100 ml of methyl tert-butyl ether. Combined organic extracts were washed once with 100 ml of water, dried using sodium sulfate, filtered and evaporated to give a residue, giving 4'-but-3-enylidene-4-vinylbicyclohexyl.

Provenance & Evidence