HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 173967Generated: October 27, 2026
Dimethyl Sulfoxide → 5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[6-(2,2-difluoro-2-phenylethoxy)hexylamino]ethyl]-8-phenylmethoxy-1H-quinolin-2-one
https://huagongshe.com/reaction/173967
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Bicarbonate Ion | HCID 769 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Iodide Ion | HCID 30165 | — |
| Reactant | 8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]quinolin-2(1H)-one | HCID 21880641 | — |
| Reactant | 6-(2,2-Difluoro-2-phenylethoxy)-1-hexanamine | HCID 50993080 | — |
| Product | 5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[6-(2,2-difluoro-2-phenylethoxy)hexylamino]ethyl]-8-phenylmethoxy-1H-quinolin-2-one | HCID 67245529 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
| ORD ID | ord-ddbeff7f6ab846eeaf306674cfaf0e17 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
